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PhyloPars: estimation of missing parameter values using phylogeny

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A wealth of information on the metabolic parameters of a species or strain can be inferred from observations on species of strains that are phylogenetically related. PhyloPars provides an efficient and statistically consistent method of combining any number of empirical observations with the phylogenetic tree to arrive at complete set of estimates for missing parameter values. Documentation is available as a complete technical description of the methodology, and as a glossary of terms used.

PhyloPars takes an incomplete feature matrix and a phylogeny as input, which you can provide below. Additionally you can configure some properties of the evolutionary model used. Click on the help icon below for concise help.

An example of PhyloPars output for a dataset for freshwater phytoplankton is available here (see also Phyto-PhyloPars). You can also use the sample dataset in a new analysis.

Feature matrix Click for help
Phylogeny Click for help
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Please cite: Bruggeman J, Heringa J and Brandt BW. (2009) PhyloPars: estimation of missing parameter values using phylogeny. Nucleic Acids Research 37: W179-W184.

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